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May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
Gene Name: | SH3-domain GRB2-like (endophilin) Interacting Protein 1 |
Synonyms: | SGIP1 |
Target Sequences: | NM_032291 NP_115667.2 Q9BQI5 |
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