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SFTPC / Surfactant Protein C
surfactant protein C
SFTPC / Surfactant Protein C is the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
| Gene Name: | surfactant protein C |
| Synonyms: | SFTPC, BRICD6, PSP-C, Pulmonary surfactant protein C, SMDP2, SFTP2, SP-C, Surfactant protein C |
| Target Sequences: | NM_003018 NP_003009.2 P11686 |
Publications (5)
1
Optimization of Variable Ventilation for Physiology, Immune Response and Surfactant Enhancement in Preterm Lambs. Bartolák-Suki E, Noble PB, Bou Jawde S, Pillow JJ, Suki B. Frontiers in physiology. 2017 8:425. (WB; Human)
[Full Text Article]
[PubMed:28690548]
[PMC:PMC5481362]
2
Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung. Yina Du, Geremy C Clair, Denise Al Alam, Soula Danopoulos, Daniel Schnell, Joseph A Kitzmiller, Ravi S Misra, Soumyaroop Bhattacharya, David Warburton, Thomas J Mariani, Gloria S Pryhuber, Jeffrey A Whitsett, Charles Ansong, Yan Xu. American journal of physiology. Lung cellular and molecular physiology. 2019 September;317:L347-L360. [Full Text Article]
[PubMed:31268347]
[PMC:PMC6766718]
Related Antibodies: LS-B10952.
3
Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation. Sandra L Leibel, Rachael N McVicar, Alicia M Winquist, Walter D Niles, Evan Y Snyder. Current protocols in stem cell biology. 2020 September;54:e118. [Full Text Article]
[PubMed:32640120]
[PMC:PMC7361156]
Related Antibodies: LS-B9161.
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SFTPC / Surfactant Protein C
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Publications
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(65)
Yes
(2)
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$460
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa1-33) Antibody
Mouse, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$589
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
SFTPC / Surfactant Protein C Mouse anti-Human Monoclonal (4A10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SFTPC / Surfactant Protein C Mouse anti-Human Monoclonal (5E6A9) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated
50 µg/$294; 100 µg/$360
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
50 µg/$294; 100 µg/$360
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa24-197) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa24-197) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa1-193) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa94-193) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa94-193) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Human Polyclonal (aa144-173) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa1-30) (Biotin) Antibody
Mouse
ELISA, ICC, IF, WB
Biotin Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa1-30) (FITC) Antibody
Mouse
ELISA, ICC, IF, WB
FITC Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa1-30) (APC) Antibody
Mouse
ELISA, ICC, IF, WB
APC Conjugated
200 µl/$952
SFTPC / Surfactant Protein C Rabbit anti-Mouse Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse
ELISA, ICC, IF, WB
HRP Conjugated, Azide-free
200 µl/$952
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of 67
product results
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