SF3B130 / SF3B3

splicing factor 3b, subunit 3, 130kDa

SF3B130 / SF3B3 is subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

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ELISA Kits (1)

Type

Sandwich (1)

Target

SF3B130 / SF3B3 (1)

Reactivity

Mouse (1)

Format

96-Well Strip Plate (1)

Publications

No (1)

Sample Type

Cell Lysates (1)

Tissue Homogenates (1)

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Mouse SF3B130 / SF3B3 (Sandwich ELISA) ELISA Kit - LS-F8483

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$811

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