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SERTAD3 was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to normal cell lines. This protein has also been shown to be a strong transcriptional co-activator. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.
Gene Name: | SERTA domain containing 3 |
Synonyms: | SERTAD3, SERTA domain containing 3, RBT1, RPA-binding trans-activator |
Target Sequences: | NM_013368 NP_037500.2 Q9UJW9 |
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