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SERPINE1 / PAI-1

Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

SERPINE1 / PAI-1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Family/Subfamily: Serine Protease Inhibitor
Synonyms: SERPINE1, PAI1, PLANH1, PAI-1, Serpin E1
Target Sequences: NM_000602 NP_000593.1 P05121

Publications (1)

1
BDNF-TrkB signaling through Erk1/2 MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids. Revest JM, Le Roux A, Roullot-Lacarrière V, Kaouane N, Vallée M, Kasanetz F, Rougé-Pont F, Tronche F, Desmedt A, Piazza PV. Molecular psychiatry. 2014 19:1001-9. (WB; Rat) [Full Text Article] [PubMed:24126929] [PMC:PMC4195976] Related Antibodies: LS-C81062.

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ELISA Kits (58)
Competitive EIA (2)
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Functional (6)
Sandwich (39)
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SERPINE1 / PAI-1 (58)
Human (18)
Mouse (11)
Rat (10)
Chicken (1)
Dog (2)
Guinea pig (1)
Monkey (2)
Pig (6)
Rabbit (4)
Rhesus monkey (1)
Sheep (1)
Product Group
DevKit Core (1)
DevKit DuoPlus (2)
1000 Wells (1)
12 x 8-Well Microstrips (4)
96-Well Microplate (8)
96-Well Strip Plate (43)
Antibody Pair and Standard (2)
No (58)
Biological Fluids (1)
Cell Culture Media (2)
Cell Culture Supernatants (10)
Cell Lysates (7)
Cell Supernatant (1)
Citrate Plasma (1)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (52)
Serum (40)
Tissue Extracts (1)
Tissue Homogenates (18)
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.2 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Media, Plasma, Serum, Tissue Extracts
1 Plate/$850
SERPINE1 / PAI-1 ELISA Kit
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Functional
96-Well Strip Plate
Human
0.125 - 100 U/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$850
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Biological Fluids, Plasma, Serum, Tissue Homogenates
1 Plate/$585
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates
1 Plate/$610
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates
1 Plate/$826
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
0.2 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$850
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
23 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$414
SERPINE1 / PAI-1 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rabbit
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$1,100
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$715
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$691
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.9 - 60 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,002
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$549
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.102 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$699
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
81.92 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.25 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Media, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum, Tissue Homogenates
1 Plate/$850
SERPINE1 / PAI-1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.1 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$830
SERPINE1 / PAI-1 ELISA Kit
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Functional
96-Well Strip Plate
Dog
0.2 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$850
SERPINE1 / PAI-1 ELISA Kit
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Functional
96-Well Strip Plate
Mouse
0.05 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$850
Viewing 1-25 of 58 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).