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SERPINE1 / PAI-1
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE1 / PAI-1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| Family/Subfamily: | Serine Protease Inhibitor |
| Synonyms: | SERPINE1, PAI1, PLANH1, PAI-1, Serpin E1 |
| Target Sequences: | NM_000602 NP_000593.1 P05121 |
Publications (1)
1
BDNF-TrkB signaling through Erk1/2 MAPK phosphorylation mediates the enhancement of fear memory induced by glucocorticoids. Revest JM, Le Roux A, Roullot-Lacarrière V, Kaouane N, Vallée M, Kasanetz F, Rougé-Pont F, Tronche F, Desmedt A, Piazza PV. Molecular psychiatry. 2014 19:1001-9. (WB; Rat)
[Full Text Article]
[PubMed:24126929]
[PMC:PMC4195976]
Related Antibodies: LS-C81062.
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(188)
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(187)
Target
SERPINE1 / PAI-1
(188)
Reactivity
Human
(133)
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(19)
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(47)
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(132)
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(89)
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(91)
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(5)
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(1)
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(1)
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(1)
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(24)
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monoclonal mc
(55)
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(132)
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(8)
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(25)
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(6)
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(6)
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(21)
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(19)
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(8)
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(5)
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(95)
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(8)
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(4)
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(1)
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(1)
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(1)
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(1)
Publications
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(187)
Yes
(1)
Expression System
HEK 293 Cells
(1)
SERPINE1 / PAI-1 Goat anti-Human Polyclonal (aa71-85) Antibody
Human
ELISA, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (aa31-80) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (aa300-400) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$386
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (MA-55F4C12) Antibody
Mouse, Rat, Human
Func
Unconjugated
100 µg/$516
SERPINE1 / PAI-1 Sheep anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
200 µg/$702
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (AT1C5) Antibody
Human
ELISA, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (3F2) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SERPINE1 / PAI-1 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, WB
Unconjugated
1 mg/$1,119
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (1D5) Antibody
Mouse, Human
Flo, IHC, WB
Unconjugated
100 µg/$503
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
100 µg/$429; 1 mg/$574; 10 mg/$3,956
SERPINE1 / PAI-1 Goat anti-Human Polyclonal Antibody
Human
IHC, IHC-Fr, IHC-P, RIA
Unconjugated
20 µl/$424; 100 µl/$558
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (Concentrated) (MA-33H1F7) Antibody
Human
IHC, IHC-Fr, WB
Unconjugated, Concentrated
1 ml/$638
SERPINE1 / PAI-1 Mouse anti-Human Monoclonal (8H9D4) Antibody
Pig, Human
ELISA, Neut, WB
Unconjugated
1 mg/$1,228
SERPINE1 / PAI-1 Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IP, WB
Unconjugated
100 µg/$737; 1 mg/$5,345
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SERPINE1 / PAI-1 Rabbit anti-Rat Monoclonal (Preservative Free) (001) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
SERPINE1 / PAI-1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$426; 1 ml/$570; 10 ml/$3,829
SERPINE1 / PAI-1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$686; 1 mg/$4,716
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SERPINE1 / PAI-1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$417; 1 ml/$555; 10 ml/$3,829
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