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SERPINB1

serpin peptidase inhibitor, clade B (ovalbumin), member 1

SERPINB1 is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.

Gene Name: serpin peptidase inhibitor, clade B (ovalbumin), member 1
Synonyms: SERPINB1, Anti-elastase, EI, LEI, Leukocyte elastase inhibitor, Peptidase inhibitor 2, PI-2, MNEI, ELANH2, M/NEI, PI2, Serpin B1
Target Sequences: NM_030666 NP_109591.1 P30740

Publications (2)

1
Circulating SerpinB1 levels and clinical features in patients with type 2 diabetes. Takebayashi K, Hara K, Terasawa T, Naruse R, Suetsugu M, Tsuchiya T, Inukai T. BMJ open diabetes research & care. 2016 November;4:e000274. [Full Text Article] [PubMed:27933185] [PMC:PMC5128937]
2
Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study. Mayu Kyohara, Daisuke Miyashita, Ryota Inoue, Kuniyuki Nishiyama, Takahiro Tsuno, Tomoko Okuyama, Yu Togashi, Yasuo Terauchi, Jun Shirakawa. PloS one. 2022 November;17:e0276915. [Full Text Article] [PubMed:36331940] [PMC:PMC9635728]

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Products
Antibodies (68)
Primary (68)
SERPINB1 (68)
Human (51)
Mouse (11)
Rat (15)
Chimpanzee (3)
Dog (10)
Gibbon (3)
Monkey (14)
Pig (3)
Sheep (3)
IHC (15)
IHC-P (10)
WB (60)
Flo (8)
ELISA (16)
ICC (1)
IF (4)
IP (1)
Peptide-ELISA (3)
rabbit (51)
mouse (15)
goat (2)
Product Group
IHCPlus (2)
IgG (14)
IgG1 (2)
IgG2a (4)
IgG2a,k (1)
IgG2b (6)
monoclonal mc (15)
polyclonal pc (53)
4A7 (1)
OTI1D1 (2)
OTI2B10 (2)
OTI2B4 (2)
OTI2D11 (2)
OTI3B4 (2)
OTI4B3 (2)
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APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (7)
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Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Unconjugated (33)
aa13-252 (8)
aa17-332 (8)
aa184-368 (8)
aa77-306 (8)
aa168-196 (7)
Internal (4)
aa1-379 (4)
aa215-264 (4)
aa100-379 (1)
aa130-143 (1)
aa65-80 (1)
No (68)
SERPINB1 Antibody - Anti-SERPINB1 antibody IHC staining of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SERPINB1 Goat anti-Human Polyclonal (aa130-143) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SERPINB1 Antibody - Immunofluorescent analysis of SerpinB1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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SERPINB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
SERPINB1 Antibody - Immunofluorescence analysis of HeLa cells.
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SERPINB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SERPINB1 Antibody - Western blot of SERPINB1 antibody.
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SERPINB1 Rabbit anti-Mouse Polyclonal (aa184-368) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SERPINB1 Antibody - Western blot of SERPINB1 antibody.
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SERPINB1 Rabbit anti-Mouse Polyclonal (aa184-368) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
SERPINB1 Antibody - Western blot of SERPINB1 antibody.
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SERPINB1 Rabbit anti-Mouse Polyclonal (aa184-368) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
SERPINB1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-SERPINB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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SERPINB1 Mouse anti-Human Monoclonal (aa77-306) (OTI2B4) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SERPINB1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-SERPINB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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SERPINB1 Mouse anti-Human Monoclonal (aa77-306) (Carrier-free) (OTI2B4) Antibody
Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SERPINB1 Antibody - Anti-SERPINB1 antibody IHC staining of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SERPINB1 Goat anti-Human Polyclonal (aa65-80) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SERPINB1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SERPINB1 mouse monoclonal antibody.
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SERPINB1 Mouse anti-Human Monoclonal (OTI3B4) Antibody
Dog, Rat, Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SERPINB1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SERPINB1 mouse monoclonal antibody.
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SERPINB1 Mouse anti-Human Monoclonal (aa77-306) (Carrier-free) (OTI3B4) Antibody
Dog, Rat, Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SERPINB1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SERPINB1 mouse monoclonal antibody.
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SERPINB1 Mouse anti-Human Monoclonal (OTI4B3) Antibody
Dog, Rat, Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
SERPINB1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-SERPINB1 mouse monoclonal antibody.
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SERPINB1 Mouse anti-Human Monoclonal (aa77-306) (Carrier-free) (OTI4B3) Antibody
Dog, Rat, Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SERPINB1 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.
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SERPINB1 Rabbit anti-Human Polyclonal (aa100-379) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
SERPINB1 Antibody - Anti-SERPINB1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SERPINB1.
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SERPINB1 Mouse anti-Human Monoclonal (aa77-306) (OTI1D1) Antibody
Dog, Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
SERPINB1 Antibody - Anti-SERPINB1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SERPINB1.
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SERPINB1 Mouse anti-Human Monoclonal (aa77-306) (Carrier-free) (OTI1D1) Antibody
Dog, Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
SERPINB1 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINB1 Rabbit anti-Human Polyclonal (aa1-379) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
SERPINB1 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINB1 Rabbit anti-Human Polyclonal (aa1-379) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
SERPINB1 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINB1 Rabbit anti-Human Polyclonal (aa1-379) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
50 µg/$294; 100 µg/$360
SERPINB1 Antibody - Immunohistochemistry of paraffin-embedded human skin using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SERPINB1 Rabbit anti-Human Polyclonal (aa1-379) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$294; 100 µg/$360
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SERPINB1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
SERPINB1 Antibody - Western Blot analysis of SERPINB1 expression in transfected 293T cell line by SERPINB1 monoclonal antibody (M01), clone 4A7.Lane 1: SERPINB1 transfected lysate(42.7 KDa).Lane 2: Non-transfected lysate.
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SERPINB1 Mouse anti-Human Monoclonal (4A7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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SERPINB1 Rabbit anti-Human Polyclonal (aa168-196) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SERPINB1 Mouse anti-Human Monoclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
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SERPINB1 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 68 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).