SERPINA5 / PCI

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex. Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators. In seminal plasma, inactivates several serine proteases implicated in the reproductive system. Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin. Inhibits tissue-and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization. Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract. In urine, inhibits urinary-type plasminogen activator and kallikrein activities. Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E. Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid.

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Products

ELISA Kits (18)

Type

Sandwich (15)

Sandwich CLIA (3)

Target

SERPINA5 / PCI (18)

Reactivity

Human (9)

Chicken (2)

Monkey (2)

Porcine (2)

Rabbit (2)

Sheep (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (14)

Publications

No (18)

Sample Type

Cell Culture Supernatants (1)

Plasma (9)

Serum (7)

Tissue Homogenates (1)

Urine (1)

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F6447

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$730

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F22873

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F39812

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$699

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F23765

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human SERPINA5 / PCI (CLIA) ELISA Kit - LS-F29216

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human SERPINA5 / PCI (CLIA) ELISA Kit - LS-F29776

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F27127

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

10 - 250 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human SERPINA5 / PCI (CLIA) ELISA Kit - LS-F26432

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.11 - 80 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma

Price:

1 Plate/$851

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F36114

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Chicken SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47060

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

3.125 - 200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47062

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47063

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47064

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

2.5 - 160 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Chicken SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47298

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

3.125 - 200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47299

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47300

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47301

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

Select

Rabbit SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F47302

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

2.5 - 160 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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