SEPT5 / Septin 5

septin 5

SEPT5 / Septin 5 is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

SEPT5 / Septin 5 (6)

Publications

No (6)

Tag

GST (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human SEPT5 / Septin 5 Protein (Recombinant His) - LS-G1342

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 20 µg/$261

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Human SEPT5 / Septin 5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72056

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.6 kDa

Price:

20 µg/$1,107

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Human SEPT5 / Septin 5 Protein (Recombinant GST) (Full Length) - LS-G29795

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

66.33 kDa

Price:

10 µg/$479; 25 µg/$670

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Human SEPT5 / Septin 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91299

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.6 kDa

Price:

20 µg/$150

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SEPT5 / Septin 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117821

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.6 kDa

Price:

100 µg/$494

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Human SEPT5 / Septin 5 Protein (Recombinant His) (aa77-323) - LS-G15704

Source:

E. coli

Tag:

His

Molecular Weight:

30.2 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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