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The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).
Gene Name: | Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase |
Synonyms: | SEPSECS, LP, Sec synthase, SLA/LP autoantigen, TRNP48, PCH2D, Liver-pancreas antigen, Selenocysteine synthase, Sep-tRNA:Sec-tRNA synthase, SLA-p35, Soluble liver antigen |
Target Sequences: | NM_016955 |
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