Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
SEPP1 / Selenoprotein P is a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.
Gene Name: | selenoprotein P, plasma, 1 |
Synonyms: | SEPP1, Selenoprotein P, SEP, Selenoprotein P, plasma, 1 |
Target Sequences: | NM_005410 NP_005401.3 P49908 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.