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Vector Laboratories, Inc.
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Newark, CA 94560
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SENP7
SUMO1/sentrin specific peptidase 7
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).
| Gene Name: | SUMO1/sentrin specific peptidase 7 |
| Family/Subfamily: | Protease , Cysteine C48 |
| Synonyms: | SENP7, KIAA1707, Sentrin-specific protease 7, SUMO-1-specific protease 2, SUMO-1 protease-2, SUSP2, SSP2 |
| Target Sequences: | NM_020654 NP_065705.3 Q9BQF6 |
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