SEMA4D / Semaphorin 4D / CD100

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

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Products

Proteins (12)

Type

Over-Expression Lysate (2)

Recombinant (10)

Target

SEMA4D / Semaphorin 4D / CD100 (12)

Publications

No (12)

Tag

6His, C-terminus (1)

Fc, C-terminus (4)

His (2)

His-GST-S (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (3)

Rat (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (3)

HEK 293 Cells (2)

Human Cells (3)

Mammalian Cells (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (6)

Biologically Active

Biologically active (1)

Select

Human SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant) - LS-G351

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

78.9 kDa

Price:

5 µg/$268; 20 µg/$349

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Mouse SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant His) (aa502-636) - LS-G13801

Source:

E. coli

Tag:

His

Molecular Weight:

16.4 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Human SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66921

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

96 kDa

Price:

20 µg/$1,107

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Human SEMA4D / Semaphorin 4D / CD100 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78717

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

96 kDa

Price:

20 µg/$150

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Rat SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant His-GST-S) (aa145-494) - LS-G24320

Source:

E. coli

Tag:

His-GST-S

Molecular Weight:

68.9 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant 6His, C-terminus) (Met22-Arg734) - LS-G39421

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.2kD

Price:

10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157

Select

Human SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant Fc, C-terminus) (Met22-Arg734) - LS-G39941

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

106.4kD

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627

Select

Mouse SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant Fc, C-terminus) (Phe24-Met711) - LS-G39970

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

103.4kD

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627

Select

SEMA4D / Semaphorin 4D / CD100 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115349

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

96 kDa

Price:

100 µg/$494

Select

Mouse SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant Fc, C-terminus) (Phe24-Met711) - LS-G139298

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

103.4 kDa

Price:

10 µg/$277

Select

Human SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant Fc, C-terminus) (Met22-Arg734) - LS-G139157

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

106.4 kDa

Price:

10 µg/$277

Select

Human SEMA4D / Semaphorin 4D / CD100 Protein (Recombinant His) (aa502-636) - LS-G13797

Source:

E. coli

Tag:

His

Molecular Weight:

16.2 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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