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Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration By similarity. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Gene Name: | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
Synonyms: | SEMA4C, M-Sema F, SEMAF, SEMACL1, Semaphorin-4C, KIAA1739, M-SEMA-F, SEMAI |
Target Sequences: | NM_017789 NP_060259.4 Q9C0C4 |
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