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SEMA3B / SemA belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants.
Gene Name: | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
Synonyms: | SEMA3B, SEMA, SEMA5, SEMAA, SemaV, Semaphorin A, LuCa-1, Sema A(V), Sema V, Semaphorin-3B, Semaphorin-V |
Target Sequences: | NM_004636 NP_004627.1 Q13214 |
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