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SEMA3A / Semaphorin 3A

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

SEMA3A / Semaphorin 3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Gene Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Synonyms: SEMA3A, Collapsin 1, Coll-1, Hsema-III, Hsema-I, Sema III, SEMAIII, SEMAL, Semaphorin III, Semaphorin-3A, Semaphorin-iii (hsema-i), SemD, SEMA1, Semaphorin D, COLL1, SEMAD, Semaphorin 3A, Semaphorin L, SEM3A
Target Sequences: NM_006080 NP_006071.1 Q14563

Publications (1)

1
Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation. Elisabeth M M A Andriessen, François Binet , Frédérik Fournier, Masayuki Hata, Agnieszka Dejda, Gaëlle Mawambo, Sergio Crespo-Garcia , Frédérique Pilon, Manuel Buscarlet, Karine Beauchemin, Véronique Bougie, Garth Cumberlidge, Ariel M Wilson, Steve Bourgault, Flavio A Rezende, Normand Beaulieu, Jean-Sébastien Delisle, Przemyslaw Sapieha. EMBO molecular medicine. 2021 May;13:e11754. [Full Text Article] [PubMed:33876574] [PMC:PMC8103107]

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Antibodies (58)
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SEMA3A / Semaphorin 3A (90)
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SEMA3A / Semaphorin 3A Mouse anti-Human Monoclonal (aa672-771) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$628
SEMA3A / Semaphorin 3A Antibody - IHC of SEMA3A (P737) pAb in paraffin-embedded human tonsil tissue.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal (aa702-756) Antibody
Rat, Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
SEMA3A / Semaphorin 3A Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$811
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$848
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$863
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$579
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SEMA3A / Semaphorin 3A Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
SEMA3A / Semaphorin 3A Antibody - Western blot of recombinant SEMA3A / Semaphorin 3A.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal (aa31-141) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651; 2 ml/$886; 5 ml/$1,479
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
SEMA3A / Semaphorin 3A Antibody - Western blot of extracts of various cell lines, using SEMA3A antibody.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SEMA3A / Semaphorin 3A Antibody - Western Blot; Sample: Recombinant SEMA3A, Human.
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SEMA3A / Semaphorin 3A Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$320; 200 µl/$367; 500 µl/$523; 1 ml/$602; 2 ml/$833; 5 ml/$1,365
SEMA3A / Semaphorin 3A Antibody - Western blot of recombinant SEMA3A / Semaphorin 3A.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SEMA3A / Semaphorin 3A Rabbit anti-Mouse Polyclonal (aa31-150) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525
SEMA3A / Semaphorin 3A Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
SEMA3A / Semaphorin 3A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$792
SEMA3A / Semaphorin 3A ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
13.7 - 10000 pg/ml
Chemiluminescent
Plasma, Serum, Tissue Homogenates
1 Plate/$851
SEMA3A / Semaphorin 3A Antibody - Immunohistochemistry analysis of SEMA3A antibody in paraffin-embedded human tonsil tissue.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal (aa688-737) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
SEMA3A / Semaphorin 3A Antibody - Semaphorin 3A antibody Western blot. All lanes: Anti Semaphorin 3A at 0.5 ug/ml. Lane 1: 293T Whole Cell Lysate at 40 ug. Lane 2: A549 Whole Cell Lysate at 40 ug. Lane 3: HELA Whole Cell Lysate at 40 ug. Predicted band size: 89 kD. Observed band size: 89 kD.
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SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal (aa550-771) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
SEMA3A / Semaphorin 3A Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
SEMA3A / Semaphorin 3A Rabbit anti-Human Polyclonal (aa31-141) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SEMA3A / Semaphorin 3A Antibody - Western blot of recombinant SEMA3A / Semaphorin 3A.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SEMA3A / Semaphorin 3A Rabbit anti-Rat Polyclonal (aa31-150) Antibody
Rat
WB
Unconjugated
100 µl/$328; 200 µl/$378; 500 µl/$545; 1 ml/$645; 2 ml/$879; 5 ml/$1,464
SEMA3A / Semaphorin 3A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Viewing 1-25 of 90 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).