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Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins.
Gene Name: | Sec61 alpha 1 subunit (S. cerevisiae) |
Family/Subfamily: | Transporter , General secretary pathway - Sec61 alpha |
Synonyms: | SEC61A1, HSEC61, SEC61A, Sec61 alpha, Sec61 alpha-1, Sec61 homolog, SEC61 |
Target Sequences: | NM_013336 NP_037468.1 P61619 |
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