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SEC31A / HSPC275 is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | SEC31 homolog A (S. cerevisiae) |
Synonyms: | SEC31A, ABP130, ABP125, HSPC334, HSPC275, SEC31-like 1 (S. cerevisiae), SEC31-like protein 1, SEC31-related protein A, SEC31L1, Web1-like protein, Yeast Sec31p homolog, KIAA0905 |
Target Sequences: | NM_014933 NP_055748.2 O94979 |
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