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6737 Mowry Ave
Newark, CA 94560
United States
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SDCBP / Syntenin
syndecan binding protein (syntenin)
SDCBP / Syntenin was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Gene Name: | syndecan binding protein (syntenin) |
| Synonyms: | SDCBP, Syndecan-binding protein 1, MDA-9, TACIP18, Scaffold protein Pbp1, MDA9, ST1, SYCL, Syntenin, Syntenin-1 |
| Target Sequences: | NM_005625 NP_005616.2 O00560 |
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