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SCN3B
sodium channel, voltage-gated, type III, beta subunit
Scn3b encodes one type of beta subunit found in voltage-gated sodium channels. These channels, composed of one alpha and one or two different beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. Scn3b is considered an auxiliary subunit that modulates channel gating and targeting to the plasma membrane. Scn3b has been shown to be significantly upregulated in a model of neuropathic pain.
| Gene Name: | sodium channel, voltage-gated, type III, beta subunit |
| Family/Subfamily: | Ion Channel , Sodium channel - voltage-gated |
| Synonyms: | SCN3B, KIAA1158, HSA243396, SCNB3, Sodium channel subunit beta-3, Navbeta3, Sodium channel beta-3 subunit |
| Target Sequences: | NM_018400 NP_060870.1 Q9NY72 |
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Antibodies
(13)
Proteins
(10)
Type
Over-Expression Lysate
(6)
Primary
(13)
Recombinant
(4)
Target
SCN3B
(23)
Reactivity
Human
(13)
Mouse
(12)
Rat
(11)
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(3)
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(3)
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(3)
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(3)
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(3)
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(3)
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IHC
(4)
IHC-P
(4)
WB
(13)
IF
(8)
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rabbit
(5)
mouse
(8)
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IHCPlus
(1)
Isotype
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(1)
IgG2b
(8)
Clonality
monoclonal mc
(8)
polyclonal pc
(5)
Clone
S396-29
(8)
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APC Conjugated
(1)
Atto 390 Conjugated
(1)
Atto 594 Conjugated
(1)
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(2)
FITC Conjugated
(2)
HRP Conjugated
(1)
PerCP Conjugated
(1)
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(1)
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(3)
Epitope
aa65-114
(4)
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No
(23)
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Fc
(1)
His
(1)
His, N-Terminal
(1)
Myc-DDK (Flag)
(7)
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(7)
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293T Cells
(3)
E. coli
(1)
HEK 293 Cells
(4)
Human Cells
(2)
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Purified
(2)
Low Endotoxin Level
Low endotoxin level
(2)
SCN3B Rabbit anti-Human Polyclonal (aa65-114) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SCN3B Rabbit anti-Human Polyclonal (aa65-114) (HRP) Antibody
Rabbit, Mouse, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SCN3B Rabbit anti-Human Polyclonal (aa65-114) (Biotin) Antibody
Rabbit, Mouse, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SCN3B Rabbit anti-Human Polyclonal (aa65-114) (FITC) Antibody
Rabbit, Mouse, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SCN3B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
E. coli
His, N-Terminal
50 µg/$392; 250 µg/$872; 10 µg/$286; 20 µg/$348; 100 µg/$511; 500 µg/$1,355
SCN3B Mouse anti-Human Monoclonal (S396-29) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µg/$442
SCN3B Mouse anti-Human Monoclonal (Biotin) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
Biotin Conjugated
100 µg/$475
SCN3B Mouse anti-Human Monoclonal (FITC) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
FITC Conjugated
100 µg/$472
SCN3B Mouse anti-Human Monoclonal (RPE) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
RPE Conjugated
100 µg/$477
SCN3B Mouse anti-Human Monoclonal (APC) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
APC Conjugated
100 µg/$478
SCN3B Mouse anti-Human Monoclonal (PerCP) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
PerCP Conjugated
100 µg/$478
SCN3B Mouse anti-Human Monoclonal (Atto 594) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
Atto 594 Conjugated
100 µg/$479
SCN3B Mouse anti-Human Monoclonal (Atto 390) (S396-29) Antibody
Mouse, Rat, Human
IF, WB
Atto 390 Conjugated
100 µg/$479
HEK 293 Cells
Myc-DDK (Flag)
22.1 kDa
20 µg/$1,107
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
42.5 kDa
100 µg/$843
HEK 293 Cells
Myc-DDK (Flag)
22.1 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
24.7 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
24.7 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
22.1 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
24.7 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
24.7 kDa
100 µg/$494
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
17.2 kDa
100 µg/$843
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