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This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.
Gene Name: | Human Immunodeficiency Virus type I Enhancer binding protein 2 |
Synonyms: | HIVEP2, C-myc intron binding protein 1, HIV-EP2, MBP-2, SHN2, ZAS2, ZNF40B, Transcription factor HIVEP2, C-myc intron-binding protein 1, MHC binding protein-2, MHC-binding protein 2, MIBP1, Schnurri-2 |
Target Sequences: | NM_006734 NP_006725.3 P31629 |
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