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SCG2 / Secretogranin II
secretogranin II
SCG2 / Secretogranin II is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
| Gene Name: | secretogranin II |
| Synonyms: | SCG2, Chromogranin-C, CHGC, EM66, Secretogranin II, Secretoneurin, SN, Secretogranin-2, SGII |
| Target Sequences: | NM_003469 NP_003460.2 P13521 |
Publications (1)
1
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease. Ondrej Libiger, Leslie M Shaw, Mark H Watson, Angus C Nairn, Kelly L Umaña, Michael C Biarnes, Rosa M Canet-Avilés, Clifford R Jack Jr, Yannick-André Breton, Laetitia Cortes, Daniel Chelsky, Daniel S Spellman, Susan A Baker, Nandini Raghavan, William Z Potter, Alzheimer's Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium, Longitudinal CSF Proteomics Project Team. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 December;17:1976-1987. [Full Text Article]
[PubMed:33984181]
[PMC:PMC9222372]
☰ Filters
Products
Proteins
(12)
Type
Over-Expression Lysate
(2)
Recombinant
(10)
Target
SCG2 / Secretogranin II
(12)
Application
SDS-PAGE
(1)
Publications
No
(11)
Yes
(1)
Tag
6His, C-terminus
(2)
GST
(1)
GST, N-terminus
(1)
His
(1)
His, N-Terminal
(2)
His,C-terminus
(1)
His-GST
(1)
Myc-DDK (Flag)
(3)
Species
Human
(8)
Mouse
(3)
Source
293T Cells
(1)
E. coli
(4)
HEK 293 Cells
(3)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(3)
Low Endotoxin Level
Low endotoxin level
(3)
E. coli
His, N-Terminal
71.51 kDa
10 µg/$285; 50 µg/$467; 100 µg/$747; 200 µg/$932; 1 mg/$2,058; 500 µg/$1,590; 5 mg/$3,263; 2 mg/$2,246
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human SCG2 comprises 612 amino acids and has a predicted molecular mass of 70.5 kDa.
100 µg/$441
Wheat Germ Extract
GST
97.1 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
68.8kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
70.8 kDa
100 µg/$494
293T Cells
Myc-DDK (Flag)
70.8 kDa
20 µg/$150
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
68.8 kDa
10 µg/$281; 50 µg/$389
E. coli
His, N-Terminal
31.9 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
E. coli
His
19.4 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
E. coli
His-GST
52.9 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
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