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SCG2 / Secretogranin II
secretogranin II
SCG2 / Secretogranin II is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
| Gene Name: | secretogranin II |
| Synonyms: | SCG2, Chromogranin-C, CHGC, EM66, Secretogranin II, Secretoneurin, SN, Secretogranin-2, SGII |
| Target Sequences: | NM_003469 NP_003460.2 P13521 |
Publications (1)
1
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease. Ondrej Libiger, Leslie M Shaw, Mark H Watson, Angus C Nairn, Kelly L Umaña, Michael C Biarnes, Rosa M Canet-Avilés, Clifford R Jack Jr, Yannick-André Breton, Laetitia Cortes, Daniel Chelsky, Daniel S Spellman, Susan A Baker, Nandini Raghavan, William Z Potter, Alzheimer's Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium, Longitudinal CSF Proteomics Project Team. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 December;17:1976-1987. [Full Text Article]
[PubMed:33984181]
[PMC:PMC9222372]
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Microplate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
E. coli
His, N-Terminal
71.51 kDa
10 µg/$285; 50 µg/$467; 100 µg/$747; 200 µg/$932; 1 mg/$2,058; 500 µg/$1,590; 5 mg/$3,263; 2 mg/$2,246
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human SCG2 comprises 612 amino acids and has a predicted molecular mass of 70.5 kDa.
100 µg/$441
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
IHC, IP, WB
Unconjugated
200 µl/$558
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (aa246-274) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
SCG2 / Secretogranin II Mouse anti-Human Monoclonal (6B7) Antibody
Human
ELISA
Unconjugated
100 µg/$423
SCG2 / Secretogranin II Goat anti-Human Polyclonal (aa203-217) Antibody
Rabbit, Pig, Horse, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (aa31-617) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (aa272-542) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
SCG2 / Secretogranin II Mouse anti-Human Monoclonal (aa31) (OTI3F12) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SCG2 / Secretogranin II Rabbit anti-Rat Polyclonal Antibody
Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$860
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Rat, Squirrel monkey, Human
IHC, WB
Unconjugated
100 µg/$572
SCG2 / Secretogranin II Rabbit anti-Mouse Polyclonal (aa342-609) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571
SCG2 / Secretogranin II Rabbit anti-Mouse Polyclonal (aa430-586) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SCG2 / Secretogranin II Rabbit anti-Mouse Polyclonal (aa11-187) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SCG2 / Secretogranin II Mouse anti-Human Monoclonal (aa31-617) (OTI2B2) Antibody
Human
WB
Unconjugated
100 µl/$434
SCG2 / Secretogranin II Mouse anti-Human Monoclonal (aa31-617) (OTI8A3) Antibody
Human
WB
Unconjugated
100 µl/$434
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