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SBDS

Shwachman-Bodian-Diamond syndrome

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Gene Name: Shwachman-Bodian-Diamond syndrome
Synonyms: SBDS, CGI-97, SWDS
Target Sequences: NM_016038 NP_057122.2 Q9Y3A5

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SBDS (4)
No (4)
His (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
SBDS Protein - Purified recombinant protein SBDS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
28.6 kDa
20 µg/$1,107
SBDS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
28.6 kDa
20 µg/$150
SBDS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.6 kDa
100 µg/$494
SBDS Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).