SATB2

SATB homeobox 2

Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

SATB2 (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human SATB2 Protein (Recombinant GST) (Full Length) - LS-G32796

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

109 kDa

Price:

2 µg/$439

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Human SATB2 Protein (Recombinant GST, N-terminus) (aa206-294) - LS-G61961

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SATB2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85395

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.4 kDa

Price:

20 µg/$215

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SATB2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113325

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

82.4 kDa

Price:

100 µg/$710

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