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Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
Gene Name: | sphingosine-1-phosphate receptor 5 |
Family/Subfamily: | GPCR , Lysophospholipid/Lysosphingolipid |
Synonyms: | S1PR5, EDG8, Edg-8, S1P receptor Edg-8, S1P receptor 5, S1P(5) receptor, S1P5, SPPR-1, SPPR-2 |
Target Sequences: | NM_030760 NP_110387.1 Q9H228 |
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