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S100B / S100 Beta
S100 calcium binding protein B
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
| Gene Name: | S100 calcium binding protein B |
| Synonyms: | S100B, NEF, Protein S100-B, S100, S100 calcium binding protein B, S100 calcium-binding protein B, S100beta, S-100 protein beta chain, S-100 protein subunit beta, S100-B |
| Target Sequences: | NM_006272 NP_006263.1 P04271 |
Publications (3)
1
Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model. Morales I, Sanchez A, Rodriguez-Sabate C, Rodriguez M,. PloS one. 2017 12:e0185989. (WB; Human)
[Full Text Article]
[PubMed:29028815]
2
The astrocytic response to the dopaminergic denervation of the striatum. Morales I, Sanchez A, Rodriguez-Sabate C, Rodriguez M. Journal of neurochemistry. 2016 October;139:81-95. [Full Text Article]
[PubMed:27230040]
3
Neuroglial transmitophagy and Parkinson's disease. Ingrid Morales, Alberto Sanchez, Ricardo Puertas-Avendaño, Clara Rodriguez-Sabate, Adrian Perez-Barreto, Manuel Rodriguez. Glia. 2020 November;68:2277-2299. [Full Text Article]
[PubMed:32415886]
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S100B / S100 Beta
(219)
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(76)
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(57)
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(7)
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(4)
aa27-76
(4)
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(1)
aa 2-92
(1)
aa64-78
(1)
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(219)
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(9)
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(7)
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(9)
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(3)
Cancer Pathology
Cancer
S100B / S100 Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$460
Cancer Pathology
Cancer
S100B / S100 Beta Mouse anti-Human Monoclonal (9A11B9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µl/$615
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$764
Sandwich
96-Well Strip Plate
Rat
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
Sandwich
96-Well Microplate
Pig
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
Sandwich
96-Well Microplate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Sandwich
96-Well Microplate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
E. coli
6His, N-terminus
12.5 kDa
50 µg/$315; 100 µg/$365
Sandwich
96-Well Microplate
Mouse
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
S100B / S100 Beta Mouse anti-Bovine Monoclonal (SA-12) Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µg/$460
S100B / S100 Beta Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
IHC, WB
FITC Conjugated
200 µl/$952
S100B / S100 Beta Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
S100B / S100 Beta Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Cancer Pathology
S100B / S100 Beta Goat anti-Human Polyclonal (Internal Region) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
E. coli
His
12.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
S100B / S100 Beta Rabbit anti-Human Monoclonal (Preservative Free) (244) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
100 µl/$412
S100B / S100 Beta Mouse anti-Human Monoclonal (Preservative Free) (1G8-C10-H8-B8) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
S100B / S100 Beta Mouse anti-Human Monoclonal (Preservative Free) (Biotin) (1G8-C10-H8-B8) Antibody
Human
ELISA
Biotin Conjugated, Preservative Free
50 µg/$343
S100B / S100 Beta Mouse anti-Human Monoclonal (aa1-92) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$323; 200 µl/$372; 500 µl/$533; 1 ml/$620; 2 ml/$853; 5 ml/$1,411
S100B / S100 Beta Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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