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S100A7 / Psoriasin

S100 calcium binding protein A7

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

Gene Name: S100 calcium binding protein A7
Synonyms: S100A7, PSOR1, Psoriasin, Protein S100-A7, Psoriasin 1, S100A7c
Target Sequences: NM_002963 NP_002954.2 P31151

Publications (1)

1
Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment. Sakurai M, Miki Y, Takagi K, Suzuki T, Ishida T, Ohuchi N, Sasano H. Breast cancer research : BCR. 2017 19:70. (ICC; Human) [Full Text Article] [PubMed:28629450] [PMC:PMC5477117] Related Antibodies: LS-B2057.

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Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
S100A7 / Psoriasin (10)
No (10)
GST (1)
His (2)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (3)
Bovine (1)
Human (7)
Mouse (1)
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
S100A7 / Psoriasin Protein - Recombinant S100 Calcium Binding Protein A7 By SDS-PAGE
Select
E. coli
His
12.7 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
S100A7 / Psoriasin Protein
Select
E. coli
His, N-Terminal
100 µg/$361; 500 µg/$739; 20 µg/$261
S100A7 / Psoriasin Protein - Purified recombinant protein S100A7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
11.3 kDa
20 µg/$1,107
S100A7 / Psoriasin Protein - Recombinant S100 Calcium Binding Protein A7 By SDS-PAGE
Select
E. coli
His
14.4 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
S100A7 / Psoriasin Protein - Recombinant  S100 Calcium Binding Protein A7 By SDS-PAGE
Select
E. coli
His-GST
43.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
S100A7 / Psoriasin Protein - 12.5% SDS-PAGE of human S100A7 stained with Coomassie Blue
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Wheat Germ Extract
GST
36.85 kDa
10 µg/$479; 25 µg/$670
S100A7 / Psoriasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
11.3 kDa
20 µg/$150
S100A7 / Psoriasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
11.3 kDa
100 µg/$494
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
11.5 kDa
10 µg/$288; 50 µg/$436
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
11.5kD
10 µg/$288; 50 µg/$442; 500 µg/$1,377; 1 mg/$1,765
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).