RTN4 / Nogo

reticulon 4

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.

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Products

Proteins (13)

Type

Over-Expression Lysate (8)

Recombinant (5)

Target

RTN4 / Nogo (13)

Application

SDS-PAGE (1)

Publications

No (13)

Tag

GST (2)

GST, N-terminus (1)

Myc-DDK (Flag) (10)

Species

Human (9)

Source

293T Cells (4)

E. coli (1)

HEK 293 Cells (6)

Wheat Germ Extract (2)

Purification

Purified (2)

Biologically Active

Biologically active (1)

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Human RTN4 / Nogo Protein (Recombinant GST, N-terminus) (Met1-Val185) - LS-G50868

Source:

E. coli

Tag:

GST, N-terminus

Application:

SDS-PAGE

Biological Activity:

Biologically active

Molecular Weight:

The recombinant human RTN4/GST chimera consists of 417 amino acids and has a predicted molecular mass of 46.2 kDa. It migrates as an approxiamtely 48 kDa band in SDS-PAGE under reducing conditions.

Price:

100 µg/$441

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Human RTN4 / Nogo Protein (Recombinant GST) (Full Length) - LS-G34669

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

47.63 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RTN4 / Nogo Protein (Recombinant GST) (Full Length) - LS-G34671

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

156.3 kDa

Price:

2 µg/$439

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Human RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83834

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.8 kDa

Price:

20 µg/$215

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Human RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83835

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.2 kDa

Price:

20 µg/$150

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Human RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83836

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.8 kDa

Price:

20 µg/$215

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Human RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83837

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.1 kDa

Price:

20 µg/$150

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Human RTN4 / Nogo Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69098

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.1 kDa

Price:

20 µg/$1,107

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Human RTN4 / Nogo Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69099

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.2 kDa

Price:

20 µg/$1,107

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RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127154

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.8 kDa

Price:

100 µg/$710

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RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111096

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.8 kDa

Price:

100 µg/$710

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RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100957

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

22.2 kDa

Price:

100 µg/$494

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RTN4 / Nogo Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102712

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.1 kDa

Price:

100 µg/$494

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