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RTCB / C22orf28
RNA 2',3'-cyclic phosphate and 5'-OH ligase
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
| Gene Name: | RNA 2',3'-cyclic phosphate and 5'-OH ligase |
| Synonyms: | RTCB, Ankyrin repeat domain 54, C22orf28, DJ149A16.6, HSPC117, FAAP, RP1-149A16.6 |
| Target Sequences: | NM_014306 NP_055121.1 Q9Y3I0 |
Publications (2)
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