RSPO3

R-spondin 3

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

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Products

ELISA Kits (7)

Type

Custom (1)

Sandwich (6)

Target

RSPO3 (7)

Reactivity

Human (4)

Mouse (3)

Format

96-Well Microplate (1)

96-Well Strip Plate (6)

Publications

No (7)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

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Human RSPO3 (Sandwich ELISA) ELISA Kit - LS-F7210

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$792

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Human RSPO3 (Sandwich ELISA) ELISA Kit - LS-F39944

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$901

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Mouse RSPO3 (Sandwich ELISA) ELISA Kit - LS-F53366

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

4.7 - 300 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$897

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Mouse RSPO3 (Sandwich ELISA) ELISA Kit - LS-F39943

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$901

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Human RSPO3 (Sandwich ELISA) ELISA Kit - LS-F31682

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

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Mouse RSPO3 (Sandwich ELISA) ELISA Kit - LS-F31745

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates

Price:

1 Plate/$624

Select

Human RSPO3 (Custom ELISA) ELISA Kit - LS-F50708

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$823

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