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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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RSPO3
R-spondin 3
Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
| Gene Name: | R-spondin 3 |
| Synonyms: | RSPO3, CRISTIN1, HRspo3, HPWTSR, R-spondin 3, Protein with TSP type-1 repeat, R-spondin 3 homolog, THSD2, PWTSR, R-spondin-3, Roof plate-specific spondin-3 |
| Target Sequences: | NM_032784 NP_116173.2 Q9BXY4 |
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Antibodies
(31)
Type
Primary
(31)
Target
RSPO3
(31)
Reactivity
Human
(30)
Mouse
(7)
Rat
(4)
Chimpanzee
(3)
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(8)
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IHC
(6)
IHC-P
(2)
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(24)
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(8)
ICC
(1)
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(2)
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(1)
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(2)
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rabbit
(23)
mouse
(6)
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(1)
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(1)
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IgG
(10)
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(6)
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(1)
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monoclonal mc
(7)
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(24)
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400404
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(1)
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(1)
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(3)
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(3)
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(1)
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(1)
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(3)
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(3)
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(1)
Unconjugated
(18)
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aa22-272
(17)
aa202-251
(4)
aa214-248
(1)
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No
(31)
RSPO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
Unconjugated
0.1 mg/$460
RSPO3 Mouse anti-Human Monoclonal (aa22-272) (OTI3A9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RSPO3 Mouse anti-Human Monoclonal (aa22-272) (Carrier-free) (OTI3A9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RSPO3 Rat anti-Mouse Monoclonal (400404) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$884
RSPO3 Rabbit anti-Human Polyclonal (aa22-272) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$404
RSPO3 Mouse anti-Human Monoclonal (aa22-272) (3D5) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$485
RSPO3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
RSPO3 Rabbit anti-Human Polyclonal (aa22-272) (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
RSPO3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
RSPO3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
RSPO3 Rabbit anti-Human Polyclonal (aa22-272) Antibody
Pig, Human
WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
RSPO3 Rabbit anti-Human Polyclonal (aa22-272) (APC) Antibody
Pig, Human
WB
APC Conjugated
100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703
RSPO3 Mouse anti-Human Monoclonal (aa22-272) (Carrier-free) (3D5) Antibody
Human
IHC
Unconjugated, Carrier-free
100 µg/$511
RSPO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RSPO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
RSPO3 Rabbit anti-Human Polyclonal (aa214-248) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
RSPO3 Mouse anti-Human Monoclonal (aa22-272) (OTI4G10) Antibody
Human
WB
Unconjugated
100 µl/$434
RSPO3 Mouse anti-Human Monoclonal (aa22-272) (Carrier-free) (OTI4G10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
RSPO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
RSPO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
RSPO3 Rabbit anti-Human Polyclonal (aa202-251) Antibody
Human
WB
Unconjugated
100 µl/$424
RSPO3 Rabbit anti-Human Polyclonal (aa202-251) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
RSPO3 Rabbit anti-Human Polyclonal (aa202-251) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
RSPO3 Rabbit anti-Human Polyclonal (aa202-251) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
RSPO3 Sheep anti-Human Polyclonal (aa22-272) Antibody
Human
Neut
Unconjugated
100 µg/$930
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of 31
product results
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