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RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
Gene Name: | ribonucleotide reductase M2 |
Synonyms: | RRM2, Ribonucleotide reductase M2, RR2, RR2M |
Target Sequences: | NM_001034 NP_001025.1 P31350 |
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