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Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
Gene Name: | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
Family/Subfamily: | Protein Kinase , RSK |
Synonyms: | RPS6KA2, HU-2, MAPKAPK-1c, MAPKAPK1C, p90 ribosomal s6 kinase 3, p90RSK2, Pp90RSK3, Ribosomal S6 kinase 3, RSK-3, S6K-alpha, p90-RSK3, RSK, RSK3, S6K-alpha-2, S6K-alpha2, MAPKAP kinase 1c, p90-RSK 2 |
Target Sequences: | NM_021135 NP_066958.2 Q15349 |
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