RPS3 / Ribosomal Protein S3

ribosomal protein S3

Involved in translation as a component of the 40S small ribosomal subunit (PubMed:8706699). Has endonuclease activity and plays a role in repair of damaged DNA (PubMed:7775413). Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (PubMed:15707971). Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (PubMed:14706345). Has also been shown to bind with similar affinity to intact and damaged DNA (PubMed:18610840). Stimulates the N-glycosylase activity of the base excision protein OGG1 (PubMed:15518571). Enhances the uracil excision activity of UNG1 (PubMed:18973764). Also stimulates the cleavage of the phosphodiester backbone by APEX1 (PubMed:18973764). When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage (PubMed:23911537). Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide (PubMed:17049931). Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes (PubMed:18045535). Represses its own translation by binding to its cognate mRNA (PubMed:20217897). Binds to and protects TP53/p53 from MDM2-mediated ubiquitination (PubMed:19656744). Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization (PubMed:23131551). Involved in induction of apoptosis through its role in activation of CASP8 (PubMed:14988002). Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5 (PubMed:20605787). Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation (PubMed:22510408).

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Products

Antibodies (34)

Type

Primary (34)

Target

RPS3 / Ribosomal Protein S3 (34)

Reactivity

Human (34)

Mouse (22)

Rat (20)

Bovine (7)

Chicken (1)

Dog (7)

Guinea pig (6)

Horse (6)

Monkey (3)

Orangutan (3)

Pig (4)

Rabbit (6)

Xenopus (2)

Zebrafish (4)

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Application

IHC (14)

IHC-P (6)

WB (34)

ELISA (9)

ICC (3)

IF (7)

IP (5)

Peptide-ELISA (3)

Host

rabbit (31)

mouse (3)

Product Group

IHCPlus (4)

Isotype

IgG (17)

IgG1 (1)

IgG1,k (1)

IgG2a,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (31)

Clone

2A8 (1)

RP159-1 (1)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (28)

Epitope

C-Terminus (5)

aa116-165 (4)

140-220 aa, C-terminal (1)

aa1-50 (1)

aa160-209 (1)

aa171-220 (1)

aa193-243 (1)

Publications

No (34)

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IHC-plus™ RPS3 / Ribosomal Protein S3 Antibody (aa193-243) LS-B14189

(4.0) Rating

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa193-243) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ RPS3 / Ribosomal Protein S3 Antibody (clone RP159-1) LS-B13724

(4.0) Rating

Antibody:

RPS3 / Ribosomal Protein S3 Mouse anti-Human Monoclonal (RP159-1) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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RPS3 / Ribosomal Protein S3 Antibody (clone 2A8) LS-C198118

Antibody:

RPS3 / Ribosomal Protein S3 Mouse anti-Human Monoclonal (2A8) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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IHC-plus™ RPS3 / Ribosomal Protein S3 Antibody LS-B13732

(4.0) Rating

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

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RPS3 / Ribosomal Protein S3 Antibody (aa116-165) LS-C151544

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa116-165) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C75466

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$688

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RPS3 / Ribosomal Protein S3 Antibody LS-C332145

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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IHC-plus™ RPS3 / Ribosomal Protein S3 Antibody (aa1-50) LS-B14188

(4.0) Rating

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C809350

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C488998

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

RPS3 / Ribosomal Protein S3 Antibody (aa171-220) LS-C119646

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa171-220) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C751829

Antibody:

RPS3 / Ribosomal Protein S3 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$371

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C770370

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C751831

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C751826

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

RPS3 / Ribosomal Protein S3 Antibody (140-220 aa, C-terminal) LS-C385912

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (140-220 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C823700

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

RPS3 / Ribosomal Protein S3 Antibody (aa160-209) LS-C200625

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (aa160-209) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C756491

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C341431

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C770371

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C748588

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C483109

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

RPS3 / Ribosomal Protein S3 Antibody LS-C770372

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

RPS3 / Ribosomal Protein S3 Antibody (C-Terminus) LS-C146497

Antibody:

RPS3 / Ribosomal Protein S3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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