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RPRD1B

Regulation of nuclear pre-mRNA domain containing 1B

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Gene Name: Regulation of nuclear pre-mRNA domain containing 1B
Synonyms: RPRD1B, CREPT, DJ1057B20.2, NET60, C20orf77
Target Sequences: NM_021215 NP_067038.1 Q9NQG5

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Products
Antibodies (27)
Primary (27)
RPRD1B (27)
Human (26)
Mouse (9)
Rat (7)
Bat (6)
Bovine (6)
Chicken (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Hamster (6)
Horse (6)
Monkey (6)
Orangutan (3)
Pig (6)
Rabbit (6)
IHC (6)
IHC-P (3)
WB (25)
Flo (7)
ELISA (11)
ICC (1)
IF (1)
IP (1)
rabbit (22)
mouse (5)
IgG (13)
IgG1 (3)
IgG2b (1)
monoclonal mc (5)
polyclonal pc (22)
08 (1)
12 (1)
OTI1C9 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Preservative Free (2)
Unconjugated (13)
aa254-282 (7)
aa112-161 (4)
aa143-192 (4)
aa276-326 (1)
No (27)
RPRD1B Antibody - IHC of paraffin-embedded Human colon tissue using anti-RPRD1B mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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RPRD1B Mouse anti-Human Monoclonal (OTI1C9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RPRD1B Antibody - IHC of paraffin-embedded Human colon tissue using anti-RPRD1B mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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RPRD1B Mouse anti-Human Monoclonal (Carrier-free) (OTI1C9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RPRD1B Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at dilution of 1:100.
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RPRD1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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RPRD1B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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RPRD1B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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RPRD1B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
RPRD1B Antibody - Immunofluorescence staining of RPRD1B in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with mouse anti-Human RPRD1B monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-mouse IgG secondary antibody (green). Positive staining was localized to Nucleus.
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RPRD1B Mouse anti-Human Monoclonal (Preservative Free) (12) Antibody
Human
ICC, IF
Unconjugated, Preservative Free
100 µl/$412
RPRD1B Antibody - Western blot of RPR1B Antibody in Jurkat cell line lysates (35 ug/lane). RPR1B (arrow) was detected using the purified antibody.
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RPRD1B Rabbit anti-Human Polyclonal (aa254-282) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
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RPRD1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
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RPRD1B Rabbit anti-Human Polyclonal (aa276-326) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RPRD1B Antibody - Western blot of Mouse Testis. Rprd1b antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RPRD1B Rabbit anti-Mouse Polyclonal (aa112-161) Antibody
Mouse
WB
Unconjugated
100 µl/$424
RPRD1B Antibody - Western blot of Mouse Testis. Rprd1b antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RPRD1B Rabbit anti-Mouse Polyclonal (aa112-161) (HRP) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
RPRD1B Antibody - Western blot of Mouse Testis. Rprd1b antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RPRD1B Rabbit anti-Mouse Polyclonal (aa112-161) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
RPRD1B Antibody - Western blot of Mouse Testis. Rprd1b antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RPRD1B Rabbit anti-Mouse Polyclonal (aa112-161) (FITC) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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RPRD1B Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$412
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RPRD1B Mouse anti-Human Monoclonal (Preservative Free) (08) Antibody
Human
IHC-P
Unconjugated, Preservative Free
100 µl/$412
RPRD1B Antibody - RPRD1B antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RPRD1B Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
RPRD1B Antibody - RPRD1B antibody Western blot of Jurkat lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RPRD1B Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
RPRD1B Antibody - Western blot analysis of extracts of various cell lines, using rprd1b antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
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RPRD1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).