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RNF40 / STARING

Ring finger protein 40, E3 ubiquitin protein ligase

Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

Gene Name: Ring finger protein 40, E3 ubiquitin protein ligase
Synonyms: RNF40, BRE1-B, KIAA0661, RING finger protein 40, Rb-associated protein, STARING, BRE1B, RBP95
Target Sequences: NM_014771 NP_055586.1 O75150

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Products
Antibodies (24)
Primary (24)
RNF40 / STARING (24)
Human (24)
Mouse (5)
Rat (4)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Orangutan (3)
Rabbit (3)
IHC (10)
IHC-P (4)
WB (18)
ELISA (11)
ICC (1)
IF (3)
IP (2)
rabbit (24)
IgG (20)
polyclonal pc (24)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (13)
aa697-725 (7)
aa801-850 (4)
Internal (2)
aa540-590 (2)
aa600-650 (1)
No (24)
RNF40 / STARING Antibody - Immunofluorescence analysis of MCF-7 cells.
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RNF40 / STARING Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
RNF40 / STARING Antibody - Immunofluorescent analysis of RNF40 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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RNF40 / STARING Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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RNF40 / STARING Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
RNF40 / STARING Antibody - Detection of Human RNF40 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-RNF40 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa540-590) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RNF40 / STARING Antibody - RNF40 antibody ARP43165_T100-NP_055586-RNF40(ring finger protein 40) Antibody IHC of formalin-fixed, paraffin-embedded human Muscle. Positive label: Skeletal muscle cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa801-850) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
RNF40 / STARING Antibody - RNF40 antibody ARP43165_T100-NP_055586-RNF40(ring finger protein 40) Antibody IHC of formalin-fixed, paraffin-embedded human Muscle. Positive label: Skeletal muscle cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa801-850) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
RNF40 / STARING Antibody - RNF40 antibody ARP43165_T100-NP_055586-RNF40(ring finger protein 40) Antibody IHC of formalin-fixed, paraffin-embedded human Muscle. Positive label: Skeletal muscle cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa801-850) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
RNF40 / STARING Antibody - RNF40 antibody ARP43165_T100-NP_055586-RNF40(ring finger protein 40) Antibody IHC of formalin-fixed, paraffin-embedded human Muscle. Positive label: Skeletal muscle cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa801-850) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
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RNF40 / STARING Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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RNF40 / STARING Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
RNF40 / STARING Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using RNF40 Antibody at dilution of 1:100
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RNF40 / STARING Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Select
RNF40 / STARING Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
RNF40 / STARING Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
RNF40 / STARING Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa600-650) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RNF40 / STARING Antibody - Detection of Human RNF40 by Immunohistochemistry. Sample: FFPE section of human mucinous ovarian carcinoma. Antibody: Affinity purified rabbit anti-RNF40 used at a dilution of 1:250. Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1:100.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa540-590) Antibody
Human
IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
RNF40 / STARING Antibody - Western blot of RNF40 Antibody antibody pre-incubated without(lane 1) and with(lane 2) blocking peptide in HL-60 cell line lysate. RNF40 Antibody (arrow) was detected using the purified antibody.
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RNF40 / STARING Rabbit anti-Human Polyclonal (aa697-725) Antibody
Human
WB
Unconjugated
400 µl/$393
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RNF40 / STARING Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$341
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).