Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
Gene Name: | ring finger protein 216 |
Family/Subfamily: | Zinc Finger |
Synonyms: | RNF216, TRIAD3, UBCE7IP1, Ring finger protein 216, U7I1, ZIN |
Target Sequences: | NM_207111 NP_996994.1 Q9NWF9 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.