RNF128 / GRAIL

ring finger protein 128, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase that catalyzes 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with 'Lys-48' linkages and COR1A with 'Lys-63' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm; sensitizes ectoderm to respond to neural-inducing signals.

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Products

Antibodies (21)

Proteins (2)

Type

Primary (21)

Recombinant (2)

Target

RNF128 / GRAIL (23)

Reactivity

Human (21)

Mouse (9)

Rat (4)

Bovine (1)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Horse (1)

Monkey (4)

Orangutan (6)

Pig (4)

Rabbit (1)

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Application

IHC (2)

IHC-P (3)

WB (17)

ELISA (10)

Host

rabbit (21)

Product Group

IHCPlus (1)

Isotype

IgG (15)

Clonality

polyclonal pc (21)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa115-143 (7)

C-Terminus (4)

aa289-338 (4)

aa227-253 (1)

Publications

No (23)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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RNF128 / GRAIL Antibody (aa227-253) LS-C47370

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa227-253) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$386

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RNF128 / GRAIL Antibody (aa115-143) LS-C324719

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

RNF128 / GRAIL Antibody (aa115-143, Biotin) LS-C240069

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

RNF128 / GRAIL Antibody (aa115-143, FITC) LS-C240070

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

RNF128 / GRAIL Antibody (aa115-143, APC) LS-C240068

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

RNF128 / GRAIL Antibody (aa115-143, PE) LS-C240073

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

RNF128 / GRAIL Antibody (aa115-143, Azide-free, HRP) LS-C248015

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

IHC-plus™ RNF128 / GRAIL Antibody LS-B15162

(4.0) Rating

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

RNF128 / GRAIL Antibody (HRP) LS-C399787

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

RNF128 / GRAIL Antibody (Biotin) LS-C399789

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

RNF128 / GRAIL Antibody (FITC) LS-C399788

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

RNF128 / GRAIL Antibody (C-Terminus) LS-C31988

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

RNF128 / GRAIL Antibody (C-Terminus, HRP) LS-C444963

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Guinea pig, Pig, Orangutan, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

RNF128 / GRAIL Antibody (C-Terminus, Biotin) LS-C444961

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Guinea pig, Pig, Orangutan, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

RNF128 / GRAIL Antibody (C-Terminus, FITC) LS-C444962

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Guinea pig, Pig, Orangutan, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

RNF128 / GRAIL Antibody (aa115-143) LS-C158863

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa115-143) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

RNF128 / GRAIL Antibody (aa289-338) LS-C135488

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa289-338) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

RNF128 / GRAIL Antibody (aa289-338, HRP) LS-C465761

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa289-338) (HRP) Antibody

Reactivity:

Mouse, Dog, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

RNF128 / GRAIL Antibody (aa289-338, Biotin) LS-C465759

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa289-338) (Biotin) Antibody

Reactivity:

Mouse, Dog, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

RNF128 / GRAIL Antibody (aa289-338, FITC) LS-C465760

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal (aa289-338) (FITC) Antibody

Reactivity:

Mouse, Dog, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

RNF128 / GRAIL Antibody LS-C817136

Antibody:

RNF128 / GRAIL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

Human RNF128 / GRAIL Protein (Recombinant GST, N-terminus) (aa329-428) - LS-G63176

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human RNF128 / GRAIL Protein (Recombinant GST) (Full Length) - LS-G35204

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.9 kDa

Price:

10 µg/$479; 25 µg/$670

Viewing 1-23 of 23 product results

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