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Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
Gene Name: | Rho family GTPase 1 |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
Synonyms: | RND1, ARHS, GTP-binding protein, RHOS, Rho family GTPase 1, RHO6 |
Target Sequences: | NM_014470 NP_055285.1 Q92730 |
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