RNASEH1

ribonuclease H1

RNASEH1 is an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which overlaps the first initiation start codon in human. An alternately spliced transcript variant has been found which encodes a shorter isoform. This gene has three pseudogenes; two of them are at different locations of chromosome 17 and one of them is on chromosome 1q32.2.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

RNASEH1 (7)

Publications

No (7)

Tag

6His, N-terminus (2)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human RNASEH1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67715

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.9 kDa

Price:

20 µg/$1,107

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Human RNASEH1 Protein (Recombinant GST, N-terminus) (aa189-286) - LS-G63841

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RNASEH1 Protein (Recombinant GST) (Full Length) - LS-G37081

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.5 kDa

Price:

2 µg/$439

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RNASEH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99911

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.9 kDa

Price:

100 µg/$494

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Human RNASEH1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80558

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.9 kDa

Price:

20 µg/$150

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Human RNASEH1 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G137101

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

37.6 kDa

Price:

20 µg/$364; 1 mg/$1,679; 100 µg/$500

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Human RNASEH1 Protein (Recombinant 6His, N-terminus) (Ser2-Asp286) - LS-G26574

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

34 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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