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RIP1 / RALBP1

ralA binding protein 1

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Gene Name: ralA binding protein 1
Synonyms: RALBP1, 76 kDa Ral-interacting protein, DNP-SG ATPase, Ral-interacting protein 1, RalA-binding protein 1, RIP1, Rlip76 protein, RIP, RLIP1, RalA binding protein 1, RLIP76
Target Sequences: NM_006788 NP_006779.1 Q15311

Publications (2)

1
Medium-Chain Triglycerides Attenuate Liver Injury in Lipopolysaccharide-Challenged Pigs by Inhibiting Necroptotic and Inflammatory Signaling Pathways. Zhang L, Wang X, Chen S, Wang S, Tu Z, Zhang G, Zhu H, Li X, Xiong J, Liu Y. International journal of molecular sciences. 2018 November;19:pii E3697. [Full Text Article] [PubMed:30469452] [PMC:PMC6274951] Related Antibodies: LS-B8214.
2
Necroptosis Mediates Muscle Protein Degradation in a Cachexia Model of Weanling Pig with Lipopolysaccharide Challenge. Junjie Guo, Xu Qin, Yang Wang, Xiangen Li, Xiuying Wang, Huiling Zhu, Shaokui Chen, Jiangchao Zhao, Kan Xiao, Yulan Liu. International journal of molecular sciences. 2023 June;24: [Full Text Article] [PubMed:37446099] [PMC:PMC10341553] Related Antibodies: LS-B8214.

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Products
Antibodies (83)
Primary (83)
RIP1 / RALBP1 (83)
Human (65)
Mouse (30)
Rat (16)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (5)
Gibbon (3)
Goat (3)
Hamster (3)
Horse (3)
Monkey (4)
Pig (3)
Rabbit (3)
IHC (21)
IHC-P (12)
WB (77)
Flo (15)
ELISA (12)
ICC (1)
IF (17)
IP (12)
Peptide-ELISA (1)
rabbit (65)
mouse (18)
Product Group
IHCPlus (2)
IgG (18)
IgG1 (16)
IgG2a (2)
monoclonal mc (19)
polyclonal pc (64)
1H9 (2)
NOD-15 (1)
OTI11B2 (2)
OTI11C6 (2)
OTI1C8 (2)
OTI1E2 (2)
OTI2A6 (2)
OTI6C6 (2)
OTI6E8 (2)
OTI6G10 (2)
APC (5)
APC Conjugated (6)
Azide-free (1)
Biotin Conjugated (8)
Carrier-free (9)
Cy3 Conjugated (5)
Cy7 Conjugated (5)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (8)
HRP Conjugated (8)
PE Conjugated (6)
Unconjugated (35)
aa192-380 (16)
aa381-470 (8)
aa403-499 (8)
aa527-626 (8)
aa42-71 (7)
N-Terminus (4)
Asp623 (1)
aa600-650 (1)
aa605-655 (1)
No (82)
Yes (1)
RIP1 / RALBP1 Antibody - Anti-RALBP1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RIP1 / RALBP1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Kidney tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI6G10) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Kidney tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6G10) Antibody
Human
Flo, IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (1H9) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
RIP1 / RALBP1 Antibody - Anti-RALBP1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RALBP1.
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI11C6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - Anti-RALBP1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RALBP1.
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI11C6) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded breast tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI11B2) Antibody
Dog, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded breast tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI11B2) Antibody
Dog, Rat, Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI6C6) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6C6) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - IHC analysis of RALBP1 using anti-RALBP1 antibody. RALBP1 was detected in paraffin-embedded section of human ovary cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-RALBP1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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RIP1 / RALBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
RIP1 / RALBP1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI1E2) Antibody
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1E2) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Kidney tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI6E8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Kidney tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6E8) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI2A6) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-RALBP1 mouse monoclonal antibody. (Dilution 1:50).
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A6) Antibody
Human
IF, IHC, IP, WB
Unconjugated, Carrier-free
100 µg/$511
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RIP1 / RALBP1 Rabbit anti-Human Monoclonal (Asp623) (NOD-15) Antibody
Human, Monkey
IP, WB
Unconjugated
100 µl/$688
RIP1 / RALBP1 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer at dilution of 1:100
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RIP1 / RALBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
RIP1 / RALBP1 Antibody - Anti-RALBP1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RALBP1.
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (OTI1C8) Antibody
Flo, IF, WB
Unconjugated
100 µl/$434
RIP1 / RALBP1 Antibody - Anti-RALBP1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RALBP1.
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C8) Antibody
Human
Flo, IF, IP, WB
Unconjugated, Carrier-free
100 µg/$511
RIP1 / RALBP1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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RIP1 / RALBP1 Mouse anti-Human Monoclonal (Carrier-free) (1H9) Antibody
Human
Flo, IP, WB
Unconjugated, Carrier-free
100 µg/$511
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RIP1 / RALBP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
RIP1 / RALBP1 Antibody - Western blot analysis of K562 lysate using RALBP1 antibody. The lane on the left is treated with the antigen-specific peptide.
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RIP1 / RALBP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RIP1 / RALBP1 Antibody - Immunohistochemistry of paraffin-embedded rat spleen using RALBP1 antibodyat dilution of 1:100 (40x lens).
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RIP1 / RALBP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$287; 100 µl/$431
Viewing 1-25 of 83 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).