RIC8A

RIC8 guanine nucleotide exchange factor A

Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex By similarity. Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

RIC8A (4)

Publications

No (4)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human RIC8A Protein (Recombinant GST, N-terminus) (aa462-534) - LS-G63049

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RIC8A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87385

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.2 kDa

Price:

20 µg/$215

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Human RIC8A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70544

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.2 kDa

Price:

20 µg/$1,107

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RIC8A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101770

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.2 kDa

Price:

100 µg/$710

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