RHOB

ras homolog family member B

Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

RHOB (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Myc-DDK (Flag), C-terminus (1)

Species

Human (6)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human RHOB Protein (Recombinant His) - LS-G1277

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human RHOB Protein (Recombinant GST, N-terminus) (aa92-193) - LS-G57807

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human RHOB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79294

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.9 kDa

Price:

20 µg/$150

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Human RHOB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67181

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.9 kDa

Price:

20 µg/$1,107

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RHOB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116955

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.9 kDa

Price:

100 µg/$494

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Human RHOB Protein (Recombinant Myc-DDK (Flag), C-terminus) - LS-G142305

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag), C-terminus

Molecular Weight:

21.9 kDa

Price:

20 µg/$1,107

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Human RHOB Protein (Recombinant GST) (Full Length) - LS-G27515

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.5 kDa

Price:

10 µg/$479; 25 µg/$670

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