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RHOA

ras homolog family member A

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

Gene Name: ras homolog family member A
Family/Subfamily: Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806
Synonyms: RHOA, ARH12, ARHA, Aplysia ras-related homolog 12, H12, Oncogene RHO H12, Rho cDNA clone 12, RHO12, RHOH12, Ras homolog family member A, Small GTP binding protein RhoA, Transforming protein RhoA
Target Sequences: NM_001664 NP_001655.1 P61586

☰ Filters
Antibodies (41)
ELISA Kits (18)
Proteins (9)
Custom (4)
Over-Expression Lysate (2)
Primary (41)
Recombinant (7)
Sandwich (14)
RHOA (68)
Human (45)
Mouse (18)
Rat (18)
Bovine (1)
Chicken (1)
Dog (2)
Guinea pig (1)
Monkey (2)
Porcine (1)
Rabbit (1)
Sheep (1)
IHC (23)
IHC-P (8)
WB (32)
Flo (4)
ELISA (22)
ICC (2)
IF (5)
IP (1)
Peptide-ELISA (3)
rabbit (30)
mouse (11)
Product Group
IHCPlus (2)
IgG (22)
IgG1 (2)
IgG1,l (7)
monoclonal mc (11)
polyclonal pc (30)
#03 (1)
09 (1)
1B12 (1)
1C1 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (15)
APC Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (2)
Preservative Free (2)
Unconjugated (28)
pSer188 (2)
130-210 aa (1)
Arg182 (1)
C-Terminus (1)
aa1-155 (1)
aa100-150 (1)
aa144-193 (1)
p188 (1)
No (68)
Cell Lysates (3)
Plasma (7)
Serum (7)
Tissue Homogenates (4)
6His, N-terminus (1)
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GST, N-terminus (1)
His (1)
His,N-terminus (1)
Myc-DDK (Flag) (3)
Human (8)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Insect Cells (1)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (1)
RHOA Antibody - Anti-RHOA antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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RHOA Mouse anti-Human Monoclonal (1C1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
RHOA Antibody - Anti-RHOA antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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RHOA Mouse anti-Human Monoclonal (1B12) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
RHOA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
RHOA Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
RHOA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
RHOA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
RHOA Antibody - Western blot analysis of extracts of various cell lines, using RHOA antibody.
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RHOA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
RHOA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21.6 kDa
20 µg/$150
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RHOA Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC, IF
Unconjugated
100 µl/$412
RHOA Antibody - Western blot of RhoA phosphorylation expression in HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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RHOA Rabbit anti-Human Polyclonal (pSer188) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µg/$305; 100 µg/$357
RHOA Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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RHOA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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RHOA Mouse anti-Human Monoclonal (aa1-155) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
200 µg/$984
RHOA ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
39.06 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$691
RHOA Antibody - Rabbit antibody to RhoA (100-150). IHC on mouse brain (cryo section) using Rabbit antibody to RhoA at a concentration of 15 ug/ml, incubated overnight and developed with DAB Ni.
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RHOA Rabbit anti-Human Polyclonal (aa100-150) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
500 µg/$393
RHOA Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RHOA Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
RHOA Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RHOA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
RHOA Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RHOA Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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RHOA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
RHOA Antibody - Western blot of Rho A antibody
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RHOA Rabbit anti-Human Polyclonal (130-210 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RHOA Antibody - Western blot analysis of extracts from HepG2 cells, using RhoA (Ab-188) antibody.
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RHOA Rabbit anti-Human Polyclonal (p188) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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RHOA Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µl/$904
Select
RHOA Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µl/$904
Select
RHOA Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
100 µl/$904
Select
RHOA Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
100 µl/$904
Select
RHOA Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$904
Viewing 1-25 of 68 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).