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RHD

Rh blood group, D antigen

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Rh blood group, D antigen
Synonyms: RHD, Blood group Rh(D) polypeptide, CD240D antigen, D antigen (DCS), RH, Rh blood group, D antigen, RHDVA(TT), Rhesus D antigen, RHXIII, Rh polypeptide 2, RH30, Rh30a, Rh4, RhDCw, RHDel, RhK562-II, RHPII, CD240D, DIIIc, Rh blood group antigen Evans, RHCED, Rhesus blood group, D antigen, Rhesus system D polypeptide, RhII, RHPI
Target Sequences: NM_016124 NP_057208.2 Q02161

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
RHD (3)
No (3)
10His, C-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Purified (1)
RHD Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, C-terminus
47.9 kDa
100 µg/$1,801; 20 µg/$1,247
RHD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45 kDa
20 µg/$215
RHD Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).