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RGS5 is a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.
Gene Name: | regulator of G-protein signaling 5 |
Family/Subfamily: | Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling |
Synonyms: | RGS5, MST092, MSTP032, MSTP106, MST106, MST129, MSTP092, MSTP129 |
Target Sequences: | NM_003617 NP_003608.1 O15539 |
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