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Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.
Gene Name: | regulator of G-protein signaling 16 |
Family/Subfamily: | Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling |
Synonyms: | RGS16, A28-RGS14, A28-RGS14P, Retinal-specific RGS, RGSR, RGS-R, HRGS-r |
Target Sequences: | NM_002928 NP_002919.3 O15492 |
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