RGMA

repulsive guidance molecule family member a

Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.

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Products

Antibodies (23)

Proteins (14)

ELISA Kits (4)

Type

Custom (1)

Over-Expression Lysate (8)

Primary (23)

Recombinant (6)

Sandwich (3)

Target

RGMA (41)

Reactivity

Human (24)

Mouse (7)

Rat (4)

Chicken (1)

Dog (3)

Guinea pig (3)

Application

IHC (2)

WB (16)

ELISA (13)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (19)

mouse (4)

Isotype

IgG (12)

IgG2a (4)

Clonality

monoclonal mc (4)

polyclonal pc (19)

Clone

OTI1C5 (2)

OTI4G8 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (3)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

Carrier-free (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (12)

Epitope

aa390-418 (7)

aa169-424 (4)

aa20-69 (4)

Publications

No (41)

Sample Type

Cell Culture Supernatants (1)

Plasma (3)

Serum (3)

Tag

10His, N-terminus + Myc, C-terminus (1)

6His, N-terminus (2)

His (1)

MBP, N-terminus + 6His, C-terminus (1)

Myc-DDK (Flag) (9)

Species

Human (10)

Source

293T Cells (4)

Baculovirus (1)

E. coli (3)

HEK 293 Cells (5)

Human Cells (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (3)

Select

Human RGMA (Sandwich ELISA) ELISA Kit - LS-F19853

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

RGMA Antibody (aa20-69) LS-C186742

Antibody:

RGMA Rabbit anti-Mouse Polyclonal (aa20-69) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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RGMA Antibody (aa20-69, HRP) LS-C471818

Antibody:

RGMA Rabbit anti-Mouse Polyclonal (aa20-69) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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RGMA Antibody (aa20-69, Biotin) LS-C471816

Antibody:

RGMA Rabbit anti-Mouse Polyclonal (aa20-69) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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RGMA Antibody (aa20-69, FITC) LS-C471817

Antibody:

RGMA Rabbit anti-Mouse Polyclonal (aa20-69) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

RGMA Antibody (aa390-418) LS-C158842

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human RGMA (Sandwich ELISA) ELISA Kit - LS-F50346

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

12.29 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$610

Select

Mouse RGMA (Sandwich ELISA) ELISA Kit - LS-F19854

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

RGMA Antibody LS-C803826

Antibody:

RGMA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

Select

RGMA Antibody LS-C753359

Antibody:

RGMA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

RGMA Antibody (aa390-418) LS-C324641

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

RGMA Antibody (aa390-418, Biotin) LS-C268149

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

RGMA Antibody (aa390-418, FITC) LS-C268150

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

RGMA Antibody (aa390-418, APC) LS-C268148

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

RGMA Antibody (aa390-418, PE) LS-C268151

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

RGMA Antibody (aa390-418, Azide-free, HRP) LS-C268152

Antibody:

RGMA Rabbit anti-Human Polyclonal (aa390-418) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

RGMA Antibody LS-C778849

Antibody:

RGMA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$357

Select

RGMA Antibody (aa169-424, clone OTI4G8) LS-C796000

Antibody:

RGMA Mouse anti-Human Monoclonal (aa169-424) (OTI4G8) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$434

Select

RGMA Antibody (aa169-424, clone OTI4G8, Carrier-free) LS-C792831

Antibody:

RGMA Mouse anti-Human Monoclonal (aa169-424) (Carrier-free) (OTI4G8) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

RGMA Antibody LS-C399499

Antibody:

RGMA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

RGMA Antibody (HRP) LS-C399488

Antibody:

RGMA Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

RGMA Antibody (FITC) LS-C399501

Antibody:

RGMA Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

RGMA Antibody (aa169-424, clone OTI1C5) LS-C796004

Antibody:

RGMA Mouse anti-Human Monoclonal (aa169-424) (OTI1C5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

RGMA Antibody (aa169-424, clone OTI1C5, Carrier-free) LS-C792838

Antibody:

RGMA Mouse anti-Human Monoclonal (aa169-424) (Carrier-free) (OTI1C5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

RGMA Antibody LS-C488968

Antibody:

RGMA Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$302

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