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RFC4

replication factor C (activator 1) 4, 37kDa

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Gene Name: replication factor C (activator 1) 4, 37kDa
Synonyms: RFC4, Activator 1 subunit 4, A1 37 kDa subunit, Activator 1 37 kd subunit, Activator 1 37 kDa subunit, RFC37, Replication factor C subunit 4, RF-C 37 kDa subunit, RFC 37 kDa subunit
Target Sequences: BC024022 NP_002907.1 P35249

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
RFC4 (10)
No (10)
GST (1)
GST, N-terminus (1)
His, N-Terminal (2)
Myc-DDK (Flag) (6)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
RFC4 Protein - 12.5% SDS-PAGE of human RFC4 stained with Coomassie Blue
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Wheat Germ Extract
GST
66.1 kDa
10 µg/$479; 25 µg/$670
RFC4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RFC4 Protein - Purified recombinant protein RFC4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
39.5 kDa
20 µg/$1,107
RFC4 Protein - Purified recombinant protein RFC4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
39.5 kDa
20 µg/$1,107
RFC4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
39.5 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
39.5 kDa
20 µg/$150
RFC4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
39.5 kDa
20 µg/$150
RFC4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
39.5 kDa
100 µg/$494
RFC4 Protein - Recombinant Replication Factor C4 (RFC4) by SDS-PAGE
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E. coli
His, N-Terminal
27.2kDa
10 µg/$263; 50 µg/$343; 200 µg/$662; 100 µg/$530; 1 mg/$1,657; 500 µg/$1,242; 5 mg/$2,600; 2 mg/$1,832
RFC4 Protein - Recombinant Replication Factor C4 (RFC4) by SDS-PAGE
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E. coli
His, N-Terminal
27.3kDa
10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).